Oklo and Centrus to Explore Joint Venture for Advanced Nuclear Fuel
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Oklo and Centrus to Explore Joint Venture for Advanced Nuclear Fuel

The potential partnership aims to establish HALEU deconversion services at Centrus' Piketon, Ohio site.

3/10/2026
Othmane Taki
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Advanced nuclear technology firm Oklo Inc. and uranium enrichment provider Centrus Energy Corp. have announced plans to explore a potential joint venture. The collaboration would focus on establishing deconversion services for high-assay low-enriched uranium (HALEU) in Piketon, Ohio. This strategic initiative aims to fortify the domestic nuclear fuel supply chain, addressing a critical need for the next generation of nuclear reactors.


Addressing a Critical Fuel Cycle Gap

The process of deconversion is an essential step in producing fuel for advanced nuclear reactors. After uranium is enriched, it must be converted into a stable chemical form, such as uranium oxide or metal, before it can be fabricated into fuel. This potential joint venture is designed to address what many experts see as a significant bottleneck in the domestic supply chain for advanced nuclear fuels.

Strategic Co-location in Southern Ohio

The proposed facility would be situated at the Centrus site in Pike County, southern Ohio, creating a powerful synergy. This location is adjacent to Centrus's existing enrichment operations and Oklo’s planned 1.2 GW power campus. Co-locating these critical fuel cycle stages is expected to significantly improve operational efficiency, reduce transportation costs, and streamline the production of HALEU fuel.

Jacob DeWitte, CEO of Oklo, stated that developing reliable fuel-cycle capabilities is as crucial as developing the reactors themselves. Centrus President and CEO Amir Vexler echoed this sentiment, noting his company's commitment to rebuilding the U.S. nuclear fuel infrastructure. This partnership directly supports their shared vision for a more integrated and efficient domestic fuel production model to meet growing demand.

A Vision for a Centralized Deconversion Hub

The collaboration aims to establish a central hub for deconversion services that could serve the entire U.S. advanced reactor industry. Currently, numerous HALEU-fueled reactor technologies are under development, each with unique fuel requirements. A centralized facility would eliminate the need for each company to build its own deconversion line, thereby enhancing industry-wide competitiveness and reducing costs.

By consolidating this key process, the venture would also simplify the complex logistics of shipping HALEU, a specialized nuclear material. This streamlined approach is viewed as a practical solution to a major challenge hindering the large-scale deployment of advanced nuclear power. The hub would provide a reliable source of deconverted material, fostering a more stable and predictable supply chain for reactor developers.

Regulatory and Community Engagement

Oklo and Centrus plan to coordinate on regulatory matters and research and development activities. This includes engaging with U.S. federal agencies to propose effective solutions that support the co-location of enrichment and deconversion services. The companies will also work closely with federal, state, and local initiatives to facilitate the siting of the facility in Pike County.

This initiative aligns with broader regional redevelopment efforts led by the Southern Ohio Diversification Initiative (SODI). The nonprofit organization is working to repurpose thousands of acres at the former Portsmouth Gaseous Diffusion Plant. The goal is to transform the area into a modern hub for advanced manufacturing and clean energy, creating new economic opportunities for the community.


In conclusion, the prospective joint venture between Oklo and Centrus represents a pivotal and proactive step toward establishing a robust, self-sufficient U.S. nuclear fuel cycle. By concentrating on the critical deconversion stage for HALEU, the partnership seeks to remove a key barrier to the widespread deployment of advanced nuclear power. This strategic collaboration in Ohio could become a cornerstone of America's clean energy infrastructure.