BRAIN Accelerator 5.0BRAIN Accelerator 5.0
DeepTechSeedPre-seed

BRAIN Accelerator 5.0

One-year hybrid accelerator for seed-stage African DeepTech in climate & health.

Organizer: open startup international
Deadline: September 15, 2025 (in 23 days)
Category: Accelerator
Regions: Rwanda, Burundi, Liberia, Tanzania, Benin, Guinea-Bissau, Mauritania, Sudan, Central African Republic, Djibouti, South Africa, Madagascar, Tunisia, Gambia, Togo, Equatorial Guinea, Burkina Faso, Cameroon, Botswana, Mozambique, Comoros, Mauritius, Morocco, Ghana, Algeria, Chad, Cabo Verde, Namibia, Somalia, Niger, Seychelles, Congo, Zimbabwe, Senegal, Kenya, Sierra Leone, Guinea, Mali, Eritrea, South Sudan, Egypt, Gabon, Malawi, Angola, Eswatini, Uganda, Côte d'Ivoire, Nigeria, Lesotho, Ethiopia, Sao Tome & Principe, Libya, Zambia, DR Congo

BRAIN (Bridging Research and Innovation) is a Pan-African initiative that strengthens DeepTech across the continent by fostering dissemination, acceleration, and connection among scientists, entrepreneurs, and innovators. Its flagship programme, the BRAIN Accelerator, is a one-year hybrid initiative for seed-stage DeepTech startups in Africa—particularly in climate and health—offering tailored mentorship, global exposure, and investment readiness support to help ventures scale to international markets.


Programme Overview

  • Startup Phase: Seed
  • Duration: 12 months
  • Field: DeepTech (with emphasis on climate and health)
  • Location: Pan-African
  • Format: Hybrid
  • Cohorts: 4 planned
  • Application Status: Open

Programme Benefits

  • Immersive Regional Bootcamp
    • In-person training in South Africa
    • Collaboration with MIT executive MBA students and global experts
    • Intensive mentorship and ecosystem exposure
  • Tailored Startup Support
    • Customised business and technical mentorship
    • Access to international trainers and subject matter experts
  • International Immersion Opportunities
    • On-demand exposure trips to the US, France, and African markets
    • Designed to support strategic growth and expansion
  • Global Talent Networks
    • Collaboration opportunities with talent from MIT, Ecole Polytechnique, Telecom Paris, and other institutions
  • Investor and Funding Support
    • Fundraising readiness training
    • Pitching sessions, investor engagement, and deal preparation
  • Pan-African Innovation Community
    • Access to OST’s network of founders, experts, and ecosystem leaders

Eligibility Criteria

Startups applying to the BRAIN Accelerator should meet the following:

  • Incorporated in an African country
  • Strong Deep Tech innovation rooted in scientific research
  • At or near the MVP stage
  • Demonstrated pathway toward intellectual property (IP)
  • Evidence of early traction or pilot deals
  • Initial grants or early-stage funding already secured
  • Ambition to scale internationally

Additional Resources

As part of its mission, BRAIN offers resources for the African DeepTech ecosystem, including:

  • Pan-African Roundtable White Paper (in collaboration with the MIT Legatum Centre)
  • African DeepTech Ecosystem Mapping Study Report
  • Interactive Dashboard to explore innovation insights

These tools are designed to foster knowledge-sharing and accelerate DeepTech innovation across the continent.


The BRAIN Accelerator reflects a broader commitment to nurturing Africa’s next wave of DeepTech pioneers. By combining incubation, mentorship, international exposure, and investor readiness, the programme provides a strong foundation for startups addressing pressing challenges in climate and health. With its Pan-African reach and global partnerships, BRAIN is positioned to catalyse a new generation of science-led ventures with international impact.