BRAIN Accelerator 5.0BRAIN Accelerator 5.0
DeepTechSeedPre-seed

BRAIN Accelerator 5.0

One-year hybrid accelerator for seed-stage African DeepTech in climate & health.

Organizer: open startup international
Deadline: October 16, 2025
Category: Accelerator

BRAIN (Bridging Research and Innovation) is a Pan-African initiative that strengthens DeepTech across the continent by fostering dissemination, acceleration, and connection among scientists, entrepreneurs, and innovators. Its flagship programme, the BRAIN Accelerator, is a one-year hybrid initiative for seed-stage DeepTech startups in Africa—particularly in climate and health—offering tailored mentorship, global exposure, and investment readiness support to help ventures scale to international markets.


Programme Overview

  • Startup Phase: Seed
  • Duration: 12 months
  • Field: DeepTech (with emphasis on climate and health)
  • Location: Pan-African
  • Format: Hybrid
  • Cohorts: 4 planned
  • Application Status: Open

Programme Benefits

  • Immersive Regional Bootcamp
    • In-person training in South Africa
    • Collaboration with MIT executive MBA students and global experts
    • Intensive mentorship and ecosystem exposure
  • Tailored Startup Support
    • Customised business and technical mentorship
    • Access to international trainers and subject matter experts
  • International Immersion Opportunities
    • On-demand exposure trips to the US, France, and African markets
    • Designed to support strategic growth and expansion
  • Global Talent Networks
    • Collaboration opportunities with talent from MIT, Ecole Polytechnique, Telecom Paris, and other institutions
  • Investor and Funding Support
    • Fundraising readiness training
    • Pitching sessions, investor engagement, and deal preparation
  • Pan-African Innovation Community
    • Access to OST’s network of founders, experts, and ecosystem leaders

Eligibility Criteria

Startups applying to the BRAIN Accelerator should meet the following:

  • Incorporated in an African country
  • Strong Deep Tech innovation rooted in scientific research
  • At or near the MVP stage
  • Demonstrated pathway toward intellectual property (IP)
  • Evidence of early traction or pilot deals
  • Initial grants or early-stage funding already secured
  • Ambition to scale internationally

Additional Resources

As part of its mission, BRAIN offers resources for the African DeepTech ecosystem, including:

  • Pan-African Roundtable White Paper (in collaboration with the MIT Legatum Centre)
  • African DeepTech Ecosystem Mapping Study Report
  • Interactive Dashboard to explore innovation insights

These tools are designed to foster knowledge-sharing and accelerate DeepTech innovation across the continent.


The BRAIN Accelerator reflects a broader commitment to nurturing Africa’s next wave of DeepTech pioneers. By combining incubation, mentorship, international exposure, and investor readiness, the programme provides a strong foundation for startups addressing pressing challenges in climate and health. With its Pan-African reach and global partnerships, BRAIN is positioned to catalyse a new generation of science-led ventures with international impact.

BRAIN Accelerator 2025 Open Startup International.